Downloads
The AlphaFold DB website currently provides bulk downloads for the 46 organisms listed below, as well as the majority of Swiss-Prot.
You can download a prediction for an individual UniProt accession by visiting the corresponding structure page (example: https://www.alphafold.ebi.ac.uk/entry/F4HVG8).
For downloading all predictions for a given species, use the download links below. Note that this option is only available on the desktop version of the site.
The uncompressed archive files (.tar) contain all the available compressed PDB and mmCIF files (.gz) for a reference proteome. In the case of proteins longer than 2700 amino acids (aa), AlphaFold provides 1400aa long, overlapping fragments. For example, Titin has predicted fragment structures named as Q8WZ42-F1 (residues 1–1400), Q8WZ42-F2 (residues 201–1600), etc. These fragments are currently only available for the human proteome in these proteome archive files, not on the website.
For downloading predictions for all the species in the tables below, visit the FTP site: https://ftp.ebi.ac.uk/pub/databases/alphafold
Compressed prediction files for model organism proteomes:
| Species | Common Name | Reference Proteome | Predicted Structures | Download |
|---|---|---|---|---|
| Arabidopsis thaliana | Arabidopsis | UP000006548 | 27,402 | Download (3,698 MB) |
| Caenorhabditis elegans | Nematode worm | UP000001940 | 19,700 | Download (2,649 MB) |
| Candida albicans | C. albicans | UP000000559 | 5,973 | Download (981 MB) |
| Danio rerio | Zebrafish | UP000000437 | 26,290 | Download (4,749 MB) |
| Dictyostelium discoideum | Dictyostelium | UP000002195 | 12,612 | Download (2,187 MB) |
| Drosophila melanogaster | Fruit fly | UP000000803 | 13,461 | Download (2,213 MB) |
| Escherichia coli | E. coli | UP000000625 | 4,370 | Download (456 MB) |
| Glycine max | Soybean | UP000008827 | 55,796 | Download (7,264 MB) |
| Homo sapiens | Human | UP000005640 | 23,586 | Download (4,938 MB) |
| Methanocaldococcus jannaschii | M. jannaschii | UP000000805 | 1,773 | Download (174 MB) |
| Mus musculus | Mouse | UP000000589 | 21,452 | Download (3,607 MB) |
| Oryza sativa | Asian rice | UP000059680 | 43,645 | Download (4,505 MB) |
| Rattus norvegicus | Rat | UP000002494 | 22,152 | Download (3,602 MB) |
| Saccharomyces cerevisiae | Budding yeast | UP000002311 | 6,055 | Download (977 MB) |
| Schizosaccharomyces pombe | Fission yeast | UP000002485 | 5,196 | Download (803 MB) |
| Zea mays | Maize | UP000007305 | 39,139 | Download (4,792 MB) |
Compressed prediction files for global health proteomes:
| Species | Common Name | Reference Proteome | Predicted Structures | Download |
|---|---|---|---|---|
| Ajellomyces capsulatus | Ajellomyces capsulatus | UP000001631 | 9,199 | Download (1,363 MB) |
| Brugia malayi | Brugia malayi | UP000006672 | 10,972 | Download (1,635 MB) |
| Campylobacter jejuni | C. jejuni | UP000000799 | 1,620 | Download (175 MB) |
| Cladophialophora carrionii | Cladophialophora carrionii | UP000094526 | 11,170 | Download (1,729 MB) |
| Dracunculus medinensis | Dracunculus medinensis | UP000274756 | 10,834 | Download (1,364 MB) |
| Fonsecaea pedrosoi | Fonsecaea pedrosoi | UP000053029 | 12,509 | Download (2,014 MB) |
| Haemophilus influenzae | H. influenzae | UP000000579 | 1,660 | Download (175 MB) |
| Helicobacter pylori | H. pylori | UP000000429 | 1,540 | Download (166 MB) |
| Klebsiella pneumoniae | K. pneumoniae | UP000007841 | 5,727 | Download (559 MB) |
| Leishmania infantum | L. infantum | UP000008153 | 7,924 | Download (1,508 MB) |
| Madurella mycetomatis | Madurella mycetomatis | UP000078237 | 9,561 | Download (1,537 MB) |
| Mycobacterium leprae | Mycobacterium leprae | UP000000806 | 1,602 | Download (177 MB) |
| Mycobacterium tuberculosis | M. tuberculosis | UP000001584 | 3,991 | Download (429 MB) |
| Neisseria gonorrhoeae | N. gonorrhoeae | UP000000535 | 2,106 | Download (195 MB) |
| Nocardia brasiliensis | Nocardia brasiliensis | UP000006304 | 8,398 | Download (873 MB) |
| Onchocerca volvulus | Onchocerca volvulus | UP000024404 | 12,039 | Download (1,621 MB) |
| Paracoccidioides lutzii | Paracoccidioides lutzii | UP000002059 | 8,794 | Download (1,294 MB) |
| Plasmodium falciparum | P. falciparum | UP000001450 | 5,168 | Download (1,148 MB) |
| Pseudomonas aeruginosa | P. aeruginosa | UP000002438 | 5,555 | Download (613 MB) |
| Salmonella typhimurium | S. typhimurium | UP000001014 | 4,526 | Download (477 MB) |
| Schistosoma mansoni | Schistosoma mansoni | UP000008854 | 9,735 | Download (1,802 MB) |
| Shigella dysenteriae | S. dysenteriae | UP000002716 | 3,893 | Download (373 MB) |
| Sporothrix schenckii | Sporothrix schenckii | UP000018087 | 8,652 | Download (1,519 MB) |
| Staphylococcus aureus | S. aureus | UP000008816 | 2,888 | Download (274 MB) |
| Streptococcus pneumoniae | S. pneumoniae | UP000000586 | 2,031 | Download (202 MB) |
| Strongyloides stercoralis | Strongyloides stercoralis | UP000035681 | 15,335 | Download (2,793 MB) |
| Trichuris trichiura | Trichuris trichiura | UP000030665 | 9,563 | Download (1,362 MB) |
| Trypanosoma brucei | Trypanosoma brucei | UP000008524 | 8,491 | Download (1,345 MB) |
| Trypanosoma cruzi | T. cruzi | UP000002296 | 19,036 | Download (2,959 MB) |
| Wuchereria bancrofti | Wuchereria bancrofti | UP000270924 | 12,725 | Download (1,418 MB) |
Compressed prediction files for Swiss-Prot:
| File type | Predicted Structures | Download |
|---|---|---|
| Swiss-Prot (CIF files) | 550,122 | Download (38,207 MB) |
| Swiss-Prot (PDB files) | 550,122 | Download (27,257 MB) |
Full dataset download for AlphaFold Database - UniProt (214M):
The full dataset of all predictions is available at no cost and under a CC-BY-4.0 licence from Google Cloud Public Datasets. We've grouped this by single-species for ease of downloading subsets or all of the data. We suggest that you only download the full dataset if you need to process all the data with local computing resources (the size of the dataset is 23 TiB, ~1M tar files). Please see our guide for how to best download and query the data or reach out to alphafold@deepmind.com for further assistance.
Licence and attributions
Data is available for academic and commercial use, under a CC-BY-4.0 licence.
EMBL-EBI expects attribution (e.g., in publications, services, or products) for any of its online services, databases, or software in accordance with good scientific practice.
If you make use of an AlphaFold prediction, please cite the following papers:
Fleming J. et al. AlphaFold Protein Structure Database and 3D-Beacons: New Data and Capabilities. Journal of Molecular Biology, (2025)
Jumper, J et al. Highly accurate protein structure prediction with AlphaFold. Nature (2021)
If you use data from AlphaMissense in your work, please cite the following paper:
AlphaMissense Copyright (2023) DeepMind Technologies Limited.
AlphaFold Data provided by Google DeepMind:
AlphaFold Data Copyright (2022) DeepMind Technologies Limited.
Feedback and questions
If you want to share feedback on an AlphaFold structure prediction, please consider using the feedback buttons at the top of each structure page. If you have any questions that are not covered in the FAQs, please contact alphafold@deepmind.com. If you have feedback on the website or experience any bugs, please contact alphafolddb@ebi.ac.uk.
Disclaimer
All AlphaFold and AlphaMissense Data and other information provided on this site contain predictions with varying levels of confidence, is for theoretical modelling only and caution should be exercised in its use. It is provided 'as-is' without any warranty of any kind, whether expressed or implied. For clarity, no warranty is given that use of the information shall not infringe the rights of any third party. The information is not intended to be a substitute for professional medical advice, diagnosis, or treatment, and does not constitute medical or other professional advice. The AlphaFold and AlphaMissense Data have not been validated for, and are not approved for, any clinical use.
Use of the AlphaFold Protein Structure Database is subject to EMBL-EBI Terms of Use.
